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Ukuthengiswa ngokuthe ngqo kwifektri Pregabalin CAS 148553-50-8 enomgangatho ogqwesileyo kunye nexabiso eliphantsi kwisitokhwe esikhuselekileyo kunye nokuhanjiswa kwamayeza okuphakathi.
ukucaciswa kwemveliso
| Igama lemveliso | Pregabalin |
| Inombolo yeCAS. | 148553-50-8 |
| I-EINECS No. | 159.23 |
| Ukuxinana | 1.0±0.1 g/cm3 |
| Indawo yokubilisa | 274.0±23.0 °C(Kuxelwe kwangaphambili) |
| Indawo yokunyibilika | 194-196°C |
| Indawo yokuflasha | 9℃ |
| Ifomula yemolekyuli | C8H17NO2 |
| Ubunzima bemolekyuli | 159.23 |
| Imbonakalo | Ulwelo olungenambala |
| Iimeko zokugcina | 2-8°C |
ividiyo yemveliso
Ingcaciso yeMveliso:
I-Pregabalin iyeza eliwela phantsi kweklasi ye-anticonvulsant drug. I-Pregabalin yi-derivative ye-gamma-aminobutyric acid (GABA), i-neurotransmitter kwinkqubo ye-nervous central. Ngokwesakhiwo, inxulumene ne-GABA ye-neurotransmitter ye-inhibitory, kodwa indlela yokusebenza kwayo yahlukile. Ngokubhekiselele kwiipropati zomzimba, i-pregabalin yikristale emhlophe eqinileyo. Iimpawu zayo zokunyibilika zibandakanya ukunganyibiliki ngokoqobo emanzini kunye nokunyibilika ngokukhululekileyo kwizinyibilikisi zendalo ezikwipolar. I-Pregabalin ifumaneka kwiifom zedosi yomlomo, njengee-capsules okanye iipilisi, ukusetyenziswa kweyeza.
I-Pregabalin isetyenziswa ngokuqhelekileyo ukunyanga iimeko ezahlukeneyo zonyango, kubandakanywa intlungu ye-neuropathic, i-fibromyalgia, kunye neentlobo ezithile zokubamba. Isebenzisa iziphumo zayo zonyango ngokuzibophelela kwi-alpha-2-delta subunit ye-voltage-gated calcium channels kwinkqubo ye-nervous central. Oku kubopha kumodareyitha ukungena kwe-calcium ion, ukunciphisa ukukhululwa kwee-neurotransmitters, kwaye ngaloo ndlela kunciphisa ukonwaba kweeseli zemithambo-luvo.
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