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Phenacetin CAS 62-44-2
Yintoni iPhenacetin CAS 62-44-2?
Impembelelo ye-antipyretic kunye ne-analgesic ye-phenacetin isetyenziswa kakhulu njengamachiza e-antipyretic kunye ne-analgesic.
Impembelelo ye-antipyretic ye-phenacetin inamandla kune-analgesic effect, kwaye isetyenziswe kuphela njengento eluhlaza kumalungiselelo adibeneyo kunye namanye amachiza.
ukucaciswa kwemveliso
| Ukuxinana | 1.0±0.1 g/cm3 |
| Indawo yokubilisa | 323.6±44.0 °C kwi-760 mmHg |
| Indawo yokunyibilika | 133-136 °C(lit.) |
| Ifomula yemolekyuli | C10H13NO2 |
| Ubunzima bemolekyuli | 179.216 |
| Indawo yokuflasha | 149.5±28.4 °C |
| Ubunzima obuchanekileyo | 179.094635 |
| PSA | 38.33000 |
| LogP | 2.01 |
| Imbonakalo | Umgubo wekristale omhlophe |
| Imeko yokugcina | Gcina kwi-2-10 ° C |
ividiyo yemveliso
Ukusetyenziswa kweMveliso
Iimpembelelo ze-antipyretic kunye ne-analgesic ye-phenacetin zifana nezo ze "acetylsalicylic acid". Isetyenziswa kakhulu njenge-antipyretic kunye ne-analgesic. Inesiphumo esicothayo kwaye sihlala ixesha elide kwaye iyasebenza ekunyangeni intloko ebuhlungu, i-neuralgia, iintlungu zamalungu kunye nomkhuhlane. ,
Isetyenziswa njengezinto eziluhlaza ukulungiselela amalungiselelo adibeneyo namanye amachiza. Ihlala idityaniswa ne-aspirin kunye ne-caffeine ukwenza i-aspirin edibeneyo, esetyenziselwa ukunyanga imikhuhlane kunye nengqele. Ukuba inani elincinci le-chlorpheniramine lifakwe kwiziyobisi ezingentla, iipilisi ze-chlorpheniramine nazo zingenziwa, ezingasetyenziselwa ukunyanga umkhuhlane, intloko, i-neuralgia, intlungu ye-rheumatic, njl.
I-Phenacetin ngokwayo ayinayo i-antipyretic kunye ne-analgesic effects. Emzimbeni, i-metabolized kwaye idibaniswe kwi-acetaminophen, eyi-paracetamol, ukusebenzisa i-antipyretic kunye ne-analgesic effects.
Impembelelo ye-synergistic yokudibanisa i-phenacetin kunye ne-salicylates iphakamisa umphumo we-analgesic. Ngokweklinikhi, isetyenziselwa kakhulu unyango lwe-antipyretic kunye ne-analgesic kwizilwanyana ezincinci. Le mveliso ikwayinxalenye yeetafile ze-APC. Inkqubo ye-vivo: Ifumaneka ngokulula xa ithathwa ngomlomo kwaye ibonisa iziphumo ze-antipyretic kunye ne-analgesic. Le mveliso kunye ne-metabolite yayo ye-paracetamol ineempembelelo ze-antipyretic. Ngenxa yokuba xa i-enzyme inhibitors isetyenziselwa ukukhusela i-phenacetin ukuba iguqulwe ibe yi-paracetamol, isengabonisa imiphumo ebalulekileyo ye-antipyretic. Ngoko ke, umphumo we-antipyretic owenzeka emva kokulawulwa kwemveliso yentambo ayibangelwa kuphela yimveliso esebenzayo yeparacetamol.
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