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I-Phenacetin CAS 62-44-2 iNtengiso ngokuthe ngqo evela eChina Umgangatho oPhezulu oKhuselekileyo wokuhanjiswa kweNqanaba eliPhezulu labaThengi baThenga kwakhona ngokuthe ngcembe.
Ingcaciso yeMveliso
I-Phenacetin, isithomalalisi-ntlungu, yaba lichiza lokuqala lehlabathi elenziwe lamayeza. Yayiyenye yeentlungu zokuqala ezingazange zithathwe kwi-opium ngelixa kwangaxeshanye zingekho iimpawu ezichasayo. I-Phenacetin yaphuhliswa ngo-1878 ngusokhemisti waseMelika, uHarmon Northrop Morse. Yaziswa kwimarike yamachiza kwi-1887. Nangona kunjalo, yarhoxiswa ngo-1983 e-United States ngenxa yamanqanaba angamkelekanga e-nephritis ye-interstitial kwizigulane kunye neengozi ezinokuthi zibe khona ze-tumorigenicity. Njengase-United States, amazwe amaninzi aseNtshona awazange avimbe i-phenacetin ekuthengiseni kude kube yi-1983. I-Phenacetin inxalenye ye-APC (aspirin-phenacetin-caffeine).
ividiyo yemveliso
Isicelo seMveliso
I-Phenacetin yayisetyenziswa njengechiza le-analgesic kunye nokunciphisa umkhuhlane kwiyeza lomntu kunye neyeza lezilwanyana iminyaka emininzi de yabandakanyeka kwisifo sezintso (nephropathy) ngenxa yokusetyenziswa kakubi kwe-analgesics kwaye yarhoxiswa kwimarike. I-Phenacetin nayo yayisetyenziswa ngaphambili njenge-stabilizer ye-hydrogen peroxide kumalungiselelo okuhlamba iinwele.
I-Phenacetin yayisetyenziswa njengechiza le-analgesic kunye nokunciphisa umkhuhlane kwiyeza lomntu kunye neyeza lezilwanyana iminyaka emininzi de yabandakanyeka kwisifo sezintso (nephropathy) ngenxa yokusetyenziswa kakubi kwe-analgesics kwaye yarhoxiswa kwimarike. I-Phenacetin nayo yayisetyenziswa ngaphambili njenge-stabilizer ye-hydrogen peroxide kumalungiselelo okuhlamba iinwele.
I-Phenacetin isetyenziswa kakhulu njenge-antipyretic analgesic, eneziphumo ezicothayo nezihlala zihleli, ukunyanga intloko ebuhlungu, i-neuralgia, iintlungu zamalungu, kunye nomkhuhlane, kunye nokumelana buthathaka nokudumba nokudumba. Ngenxa yeziphumo ebezingalindelekanga ezinobuthi kunye nophuhliso olukhawulezileyo lwamachiza afanayo, nangona kunjalo, ayisasetyenziswa yodwa, kuphela njengento ekrwada ngokudityaniswa namanye amachiza. Ngokuqhelekileyo kudityaniswe ne-aspirin kunye ne-caffeine ukwenza i-aspirin encinci enetyhefu esetyenziselwa ukunyanga ingqele eqhelekileyo. Unokwenza iipilisi ezibandayo ze-chlorpheniramine ngokudibanisa inani elincinci le-chlorpheniramine kwikhompawundi engentla, esetyenziselwa ukunyanga umkhuhlane kunye nentloko, i-neuralgia, i-rheumatism, njl.
ukucaciswa kwemveliso
| Ukuxinana | 1.0±0.1 g/cm³ |
| Indawo yokubilisa | 323.6±44.0 °C kwi-760 mmHg |
| Indawo yokunyibilika | 133-136 °C(lit.) |
| Ifomula yeemolekyuli | C10H13NO2 |
| Ubunzima beMolekyuli | 179.216 |
| Indawo yokuflasha | 149.5±28.4 °C |
| IMisa ngqo | 179.094635 |
| PSA | 38.33000 |
| LogP | 2.01 |
| Uxinzelelo lomphunga | 0.0±0.7 mmHg ku-25°C |
| Isalathiso seRefraction | 1.506 |
Iphakheji
| Kwifom yomgubo | Ibhegi yeplastiki kunye nebhegi yefoyile yealuminiyam | |
| >=25kg | Umgqomo wekhadibhodi kunye neengxowa ezicacileyo ezakhelwe ngaphakathi kunye neengxowa ze-aluminium foil | |
| Iimveliso eziqhelekileyo zeekhemikhali | Ithunyelwe ngokuthe ngqo kwiingxowa | |
| Kwiifom zolwelo | Iindidi ezahlukeneyo zemibhobho yeekhemikhali | |
| Iimveliso zexabiso eliphezulu kunye nendalo ye-R&D | Ithunyelwe kwiibhotile ezine-fluorinated |
Ukuhambisa ngenqanawe
Iiodolo ezifakwe ngaphambi kwentsimbi ye-17:00 ukususela ngoMvulo ukuya ngoLwesihlanu ziya kuthunyelwa ngokubanzi zisuka kumzi-mveliso zisiwe kumhambisi wempahla kwangolo suku lunye (ngokuqhelekileyo azithunyelwa ngeempelaveki), yaye ziya kufika kumthumeli wempahla malunga neentsuku ezintathu ukuya kwezine.
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Qhagamshelana nathi
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umzi-mveliso kunye neWarehouse
Umzi-mveliso wethu unemveliso yonyaka ezinzileyo yeetoni ezingama-50,000 zemathiriyeli ekrwada unyaka wonke. Ikhonkco lemveliso kunye nekhonkco lokuthengisa liyaqhubeka nokuhlutha. Indawo yethu yokugcina inomthamo omkhulu womgubo kunye nesitokhwe solwelo. Siyabamkela abantu bazo zonke iinkalo zobomi ukuba baxhase kwaye basebenzisane.
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