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Dihexa CAS 1401708-83-5 China ifektri intengiso ngqo Ukuhanjiswa Ukhuseleko ngenqanawe okugqwesileyo Umgangatho ophezulu costomers ukwaneliseka Ukuhanjiswa ngokukhawuleza ixabiso elikhuphisanayo Ucoceko oluPhezulu
Ingcaciso yeMveliso
Wadibana. Ikhompawundi ifunyenwe ukuba iphucule ngokunamandla ukusebenza kwengqondo kwiimodeli zezilwanyana ze-Alzheimer's-efana nokukhubazeka kwengqondo. Kuvavanyo lomsebenzi we-neurotrophic, i-Dihexa yafunyaniswa iyimiyalelo esixhenxe yobukhulu obunamandla kune-brain-derived neurotrophic factor.
ividiyo yemveliso
Isicelo seMveliso
I-N-Hexanoic-Try-Ile- (6) -amino Hexanoic amide (Dihexa) i-angiotensin IV analog njenge-procognitive / antidementia agent.
I-Dihexa, ichiza le-oligopeptide, i-analog esebenzayo ngomlomo kunye ne-blood-brain-permeable angiotensin IV. I-Dihexa ibophelela kwi-hepatocyte factor factor (HGF) kunye nobudlelwane obuphezulu (Kd = 65 pM) kwaye ikwazi ukwenza umsebenzi wayo kwi-receptor yayo, i-c-Met. I-Dihexa ibonisa umsebenzi obalaseleyo we-antidementia kwaye iphucula umsebenzi wokuqonda kwiimodeli zezilwanyana. I-Dihexa inokuba namandla onyango njengonyango lwe-Alzheimer's disease.
ukucaciswa kwemveliso
| Igama eliqhelekileyo | Dihexa |
| Inombolo yeCAS | 1401708-83-5 |
| Ukuxinana | 1.1±0.1 g/cm3 |
| Indawo yokubilisa | 866.2±65.0 °C kwi-760 mmHg |
| Ifomula yeemolekyuli | I-C27H44N4O5 |
| Ubunzima beMolekyuli | 504.662 |
LogP | 2.78 |
EINECS | 227-005-2 |
Uxinzelelo lomphunga | 0.0±0.3 mmHg ku-25°C |
Isalathiso seRefraction | 1.529 |
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