Feme e fana ka thekiso e chesang ea CAS 218949-48-5 Tesamorelin e nang le theko e phahameng ea boleng bo holimo e rekisoang ka theko e phahameng le ho fana ka ntlo le ntlo.

Timorelin e entsoe ka tatellano ea 44 ea amino acid ea human growth hormone releasing factor (GRF), e nang le 3-hexenyl e khomaretsoeng masala a eona a tyrosine N-terminal. Ke mofuta oa "hormone ea kholo" e hlahisang analog, e ke keng ea khutlisetsa secretion e tloaelehileng ea "hormone ea kholo" ka har'a vivo, empa hape e fokotsa ho eketseha ha lithane tsa visceral adipose (VAT), ho ntlafatsa dyslipidemia le boleng ba bophelo, le ho boloka botsitso bo matla. glucose ka har'a vivo. Timorelin ke analogue ea maiketsetso ea kholo ea hormone releasing factor (GRF). Joalo ka GRF ea tlhaho, e sebetsa ka har'a vitro ka ho tlama le ho kenya tšebetsong li-receptor tsa GRF. GRF ke hypothalamic regulatory polypeptide, e ka susumetsang lisele tsa kholo ea pituitary ho kopanya le ho lokolla endogenous growth hormone (GH). GH e phetha karolo ea pharmacological ka ho sebelisana le li-receptor tse khethehileng tsa lisele tse lebisitsoeng, ho akarelletsa le chondrocyte, osteoblasts, cardiomyocytes, hepatocytes le adipocytes. E loketse bakeng sa kalafo ea ho ruruha ka mpeng ho bakuli ba nang le tšoaetso ea HIV ba nang le lipodystrophy.