Iibka kulul ee warshadda CAS 218949-48-5 Tesamorelin oo leh qiimo jumlo iibka iibka kulul oo tayo sare leh iyo albaab ilaa albaab

Timorelin waxa uu ka kooban yahay 44 amino acid taxane ah oo hormoonka koritaanka bini'aadamka sii deynaya (GRF), oo leh 3- hexenyl oo ku dheggan hadhaaga tyrosine N-terminal. Waa a novel koritaanka hormone sii daayo analog factor, kaas oo aan soo celin karaa oo kaliya dheecaanka caadiga ah ee hoormoonka koritaanka in vivo, laakiin sidoo kale la yareeyo kororka unugyada adipose visceral (VAT), hagaajin dyslipidemia iyo tayada nolosha, iyo ilaalinta dheelitirka firfircoon ee gulukoosta vivo. Timorelin waa analooga synthetic ee hormoonka koritaanka hormoonka sii daaya (GRF). Si la mid ah GRF endogenous, waxay u shaqeysaa gudaha vitro iyadoo ku xiraysa oo dhaqaajisa soo-qabayaasha GRF. GRF waa polypeptide nidaamisa hypothalamic, kaas oo kicin kara unugyada hoormoonka koritaanka pituitary si ay u abuurmaan una sii daayaan hoormoonka koritaanka endogenous (GH). GH waxa ay ka ciyaartaa door farmashiyeed iyada oo la falgasha soo dhaweeyayaal gaar ah oo ah unugyada la beegsanayo, oo ay ku jiraan chondrocytes, osteoblasts, cardiomyocytes, hepatocytes iyo adipocytes. Waxay ku habboon tahay daaweynta adiposity-ga caloosha ee bukaannada qaba HIV-ga ee leh lipodystrophy.