CAS 148553-50-8 Pregabalin Shiinaha iibka tooska ah ee iibka tooska ah ee tayada sare leh ee tayada sare leh ee ku qanacsanaanta qiimaha sare ee Badbaadada Sare dhoofinta Degdega ah

Pregabalin waa daawada suuxdinta jiilka labaad (AED) oo loo yaqaan magaca sumadda Lyrica? (Pfizer, Tadworth) gudaha UK iyo USA (Pfizer, New York, NY).

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Pregabalin (Lyrica), oo ka soo jeeda GABA oo si dhow ula xidhiidha gabapentin, ayaa maray cilmi-baaris ballaaran oo ku saabsan waxtarkeeda daaweynta xaaladaha sida xanuunka guud ee walaaca (GAD), fibromyalgia, xanuunka neuropathic, iyo qalalka qayb ahaan adag. Waxay u muuqataa inay saameyn badan ku leedahay qaybta a2-δ ee kanaalada calcium ee maskaxda marka la barbar dhigo gabapentin. Pregabalin waxaa la siiyay ogolaanshaha FDA dhamaadka 2004 ee daaweynta xanuunka neuropathic xanuunka iyo suuxdinta. Sannadkii 2008, waxay noqotay daawadii ugu horreysay ee loo oggolaaday maaraynta fibromyalgia. In kasta oo pregabalin loo oggolaaday daawaynta GAD ee Midowga Yurub 2006, weli ma helin oggolaanshaha FDA ee GAD gudaha Mareykanka waqtiga qorista.

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Codsiga Alaabta

S-Enantiomer ee Pregabalin. Analoogga GABA ee loo isticmaalo sidii anticonvulsant. Anxiolytic analgesic loo isticmaalo in lagu daweeyo xanuunka neuropathic durugsan iyo fibromyalg Pregabalin waa dawada lidka-ka-hortagga ah ee loo isticmaalo xanuunka neuropathic, sida daawayn dheeri ah oo loogu talagalay suuxdinta qayb ahaan, iyo khalkhalka guud ee walaaca. Waxa loo nashqadeeyay sidii beddele ka xoog badan gabapentin. Pregabalin waxaa suuq geysa Pfizer oo hoos timaada magaca ganacsiga

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Magaca Guud	Pregabalin
Lambarka CAS	148553-50-8
Cufnaanta	1.0±0.1 g/cm3
Barta karkaraya	274.0±23.0 °C at 760 mmHg
Qaanuunka molecular	C8H17NO2
Miisaanka Molecular	159.226
PSA	63.32000
LogP	1.12
EINECS	604-639-1
Cadaadis uumiga	0.0±1.2 mmHg at 25°C
Tusmada Milicsiga	1.465