0102030405
Mugadziri Wepamusoro Kuchena 98% Peptides Powder Liraglutide CAS 204656-20-2 Peptides Powder muVials mutengo wakaderera runako peptides Zvizoro zvekushandisa.
chigadzirwa yakatarwa
| Product name | Liraglutide |
| CAS Nha. | 204656-20-2 |
| EINECS Nha. | 810-818-7 |
| Density | N/A |
| Boiling point | N/A |
| Melting point | N/A |
| Flash point | N/A |
| Molecular formula | C172H265N43O51 |
| Molecular uremu | 3751.202 |
| Chitarisiko | White Powder |
| Kuchengetedza mamiriro | -20°C |
chigadzirwa vhidhiyo
Product Description
Liraglutide (NN2211) ndeyekureba-inobata glucagon-yakafanana peptide-1 receptor agonist. Inotengeswa pasi pezita rechiratidzo Victoza, mushonga unobaiwa wakagadzirwa neNovo Nordisk wekurapa chirwere cheshuga cherudzi rwechipiri. Muna 2015, Novo Nordisk akatanga kuishambadza kuUS pasi pezita rechiratidzo liraglutide semushonga wekufutisa muvakuru vane huremu humwechete hunoenderana nehuremu.
Kushandiswa Kwezvokurapa
Liraglutide inotorwa kamwe-zuva nezuva incretin yemunhu incretin (metabolic hormone) glucagon-like peptide-1 (GLP-1), yekurapa chirwere cheshuga chechipiri kana kufutisa.
Type 2 Chirwere cheshuga
Liraglutide inovandudza kudzora kweglucose yeropa. Kunonoka kubuda mudumbu, uye kudzvanyirira prandial glucagon secretion.
Zvakafanana kune akasiyana madhigirii nemamwe maGLP-1 receptor agonists, liraglutide ine zvakanakira kupfuura mamwe echinyakare marapirwo emhando yechipiri chirwere cheshuga:
Iyo ine mukana wekudzivisa apoptosis uye kukurudzira kuvandudzwa kwemasero e beta (anoonekwa muzvidzidzo zvemhuka).
Inoderedza kudya uye inhibits huremu hwemuviri, sezvakaratidzwa mumusoro-kune-musoro kudzidza maringe neglimepiride.
Inoderedza mazinga eropa triglyceride.
Kufutisa
Liraglutide yakabvumidzwa seyakajairwa jekiseni kune yakaderedzwa-calori yekudya uye yakawedzera kuita kwemuviri kwechisingaperi uremu manejimendi muvarwere vakuru. Izvo zvakatarwa ndeyekutanga body mass index (BMI) ye30 kg/m2 kana yakakura (yakafutisa), kana 27 kg/m2 kana kupfuura (yakawandisa), pamberi pehumwe huremu-hune chekuita necomorbid mamiriro (semuenzaniso hypertension, Type 2 chirwere cheshuga mellitus, kana dyslipidemia). Mukupera kwe2014, data yakashumwa kubva kuSCALE ™ Obesity uye Prediabetes muedzo, iyo isinganzwisisiki, kaviri-mapofu, placebo-inodzorwa, muedzo wepasi rose mune vanhu vasiri vane chirwere cheshuga vane kufutisa uye vasiri vanhu vane chirwere cheshuga avo vakanyanya kuwandisa necomorbidities. Muchikamu ichi 3a kuyedzwa, pakanga paine 3,731 vatori vechikamu vakarongeka kurapwa ne liraglutide 3 mg kana placebo, zvese zvakasanganiswa nekudya uye maekisesaizi. Avo vakapedza 56-vhiki yekuedza vakawana avhareji yekurasikirwa kwe9.2%, kuenzaniswa nekuderedza 3.5% muboka re placebo.
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