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Uruganda rugurisha Pregabalin CAS 148553-50-8 hamwe nubwiza buhebuje nigiciro gito mububiko bwizewe kandi bwihuse bwo gutanga imiti hagati
ibicuruzwa
| Izina RY'IGICURUZWA | Pregabalin |
| URUBANZA No. | 148553-50-8 |
| EINECS No. | 159.23 |
| Ubucucike | 1.0 ± 0.1 g / cm3 |
| Ingingo yo guteka | 274.0 ± 23.0 ° C (Biteganijwe) |
| Ingingo yo gushonga | 194-196 ° C. |
| Ingingo ya Flash | 9 ℃ |
| Inzira ya molekulari | C8H17NO2 |
| Uburemere bwa molekile | 159.23 |
| Kugaragara | Amazi adafite ibara |
| Imiterere yo kubika | 2-8 ° C. |
videwo y'ibicuruzwa
Ibisobanuro ku bicuruzwa:
Pregabalin ni imiti igwa mucyiciro cyimiti igabanya ubukana. Pregabalin ni inkomoko ya acide gamma-aminobutyric (GABA), neurotransmitter muri sisitemu yo hagati yo hagati. Mu buryo, muburyo bujyanye no kubuza neurotransmitter GABA, ariko uburyo bwibikorwa buratandukanye. Kubireba imiterere yumubiri, pregabalin ni kristaline yera ikomeye. Ibiranga ibishishwa birimo gushiramo amazi no gushonga kubusa mumashanyarazi ya polar. Pregabalin iraboneka muburyo bwa dosiye yo mu kanwa, nka capsules cyangwa ibinini, kugirango bikoreshe imiti.
Pregabalin ikunze gukoreshwa mu kuvura indwara zitandukanye, harimo ububabare bwa neuropathique, fibromyalgia, n'ubwoko bumwe na bumwe bwo gufatwa. Ikora ingaruka zayo zo kuvura ihuza alpha-2-delta subunit ya voltage-gaze ya calcium ya calcium muri sisitemu yo hagati. Uku guhuza guhindura urujya n'uruza rwa calcium ion, kugabanya irekurwa rya neurotransmitter, bityo bikagabanya gushimisha ingirabuzimafatizo.
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