CAS 69440-99-9 Thymalfasin hamwe nisi yose ishyushye kugurisha ibicuruzwa byiza byinshi byo kugurisha hamwe no guhaza byihuse abakiriya

Thymalfasin ni ubwoko bwa poroteyine na polypeptide imisemburo ifite imikorere yo kongera ubudahangarwa bw'umubiri, ikorwa na selile epithelia selile cortex superficial na medulla ya thymus. Ni polypeptide acide igizwe na acide 28 amine. Nibisubizo byibinyabuzima bifite ibikorwa byinshi byibinyabuzima. Ikoreshwa cyane cyane mukuvura immunodeficiency, kwandura virusi nibibyimba mumavuriro. Numuti wo kumurongo wambere wo kuvura hepatite B, kandi urashobora no gukoreshwa nkumuti wongera inkingo. Ingaruka zo kuvura ziratangaje. Ifite ibyiza byibikorwa byinshi, uburozi buke ningaruka mbi nibimenyetso byinshi. Thymalfasine irashobora kongera imikorere ya selile P, igateza imbere umusaruro wa lymphocyte, igenga igipimo cyuduce twa P selile, U itandukanyirizo rya U hamwe n’umusemburo wa antibody, igashishikaza umusaruro w’ibindi bintu byitwa lymphatic antiviral na macrophage, byongera fagocytose, kandi bigateza imbere imikorere y’umubiri wa selile. abarwayi b'ibibyimba. Irashobora kandi gukuraho bagiteri, ibihumyo na virusi mu mubiri. Uburyo bushya bwa thymic bukoreshwa kuri sisitemu yimitsi no hafi ya endotelium, igira uruhare mukugenzura kwanduza synaptic ya neuron ya hippocampal. Thymalfasin igira ingaruka ku kwanduza synapses ishimishije hamwe na sisitemu ya nervice, kandi irashobora gukoreshwa mu gukumira neurotoxicity iterwa na chimiotherapie hamwe n’ubundi buryo bwo kuvura antikanseri ku barwayi ba kanseri. Thymalfasin ifite umurimo wo kugenzura gene, ishobora gutera genase ya casase cascade, igenga genoside ya cytokine hamwe na gen igenga ubudahangarwa bw'umubiri. Ingaruka-ya-thimalfasine kuri gene imeze nka reseptor gene yerekana ko thymalfasine ishobora gutera antigen itanga selile. Uruhare rwa thymidine mu mikurire y’uturemangingo tw’umubiri rugaragarira mu kugenzura-ibintu byo gukura kw ingirabuzimafatizo no kwerekana imiterere ya poroteyine ya hematopoietic.