CAS 148553-50-8 Uruganda rwa Pregabalin Ubushinwa bugurisha ibicuruzwa byiza Ubwiza buhebuje abakiriya bishimira igiciro cyiza Igiciro cyo hejuru Umutekano wohereza ibicuruzwa byihuse Gutanga vuba

Pregabalin ni igisekuru cya kabiri imiti igabanya ubukana (AED) izwi ku izina rya Lyrica? (Pfizer, Tadworth) mu Bwongereza no muri Amerika (Pfizer, New York, NY).

Twandikire

ibicuruzwa birambuye

gupakira & gutanga

Ibisobanuro ku bicuruzwa

Pregabalin (Lyrica), inkomoko ya GABA ifitanye isano rya hafi na gabapentin, yakoze ubushakashatsi bwimbitse ku kamaro kayo mu kuvura indwara nk'indwara rusange yo guhangayika (GAD), fibromyalgia, ububabare bwa neuropathique, no gufatwa igice. Birasa nkaho bigira ingaruka nziza kuri a2-δ subunit yimiyoboro ya calcium mubwonko ugereranije na gabapentin. Pregabalin yemerewe na FDA mu mpera z'umwaka wa 2004 kugira ngo avure ububabare bwa neuropathique na epilepsy. Muri 2008, ibaye imiti yambere yemejwe gucunga fibromyalgia. Nubwo pregabalin yemerewe kuvurwa GAD mu muryango w’ubumwe bw’ibihugu by’Uburayi mu 2006, ntirabona icyemezo cya FDA kuri GAD muri Amerika kugeza igihe yandikaga.

videwo y'ibicuruzwa

Gusaba ibicuruzwa

S-Enantiomer wa Pregabalin. GABA analogue ikoreshwa nka anticonvulsant. Anxiolytike analgesic ikoreshwa mu kuvura ububabare bwa neuropathique bwa peripheri na fibromyalg Pregabalin ni imiti igabanya ubukana ikoreshwa mu bubabare bwa neuropathique, nk'ubuvuzi bufatika bwo gufata igice, ndetse no muri rusange indwara yo guhangayika. Yashizweho nkumusimbuzi ukomeye wa gabapentin. Pregabalin igurishwa na Pfizer munsi yubucuruzi

ibicuruzwa

Izina Rusange	Pregabalin
Umubare CAS	148553-50-8
Ubucucike	1.0 ± 0.1 g / cm3
Ingingo	274.0 ± 23.0 ° C kuri 760 mmHg
Inzira ya molekulari	C8H17NO2
Uburemere bwa molekile	159.226
PSA	63.32000
LogP	1.12
EINECS	604-639-1
Umuvuduko w'umwuka	0.0 ± 1,2 mmHg kuri 25 ° C.
Ironderero ryo Kuvunika	1.465