0102030405
Wopanga Kuyera Kwambiri 98% Peptides Powder Liraglutide CAS 204656-20-2 Peptides Powder mu Mbale zotsika mtengo kukongola peptides Zodzikongoletsera zopangira
tsatanetsatane wazinthu
| Dzina la malonda | Liraglutide |
| CAS No. | 204656-20-2 |
| EINECS No. | 810-818-7 |
| Kuchulukana | N / A |
| Malo otentha | N / A |
| Malo osungunuka | N / A |
| pophulikira | N / A |
| Molecular formula | C172H265N43O51 |
| Kulemera kwa maselo | 3751.202 |
| Maonekedwe | Ufa Woyera |
| Zosungirako | -20 ° C |
vidiyo yamalonda
Mafotokozedwe Akatundu
Liraglutide (NN2211) ndi glucagon-ngati peptide-1 receptor agonist wanthawi yayitali. Wogulitsidwa pansi pa dzina la Victoza, ndi jakisoni wopangidwa ndi Novo Nordisk pochiza matenda amtundu wa 2. Mu 2015, Novo Nordisk adayamba kugulitsa ku US pansi pa dzina la liraglutide ngati chithandizo cha kunenepa kwambiri kwa akulu omwe ali ndi vuto limodzi lokhudzana ndi kulemera.
Ntchito Zachipatala
Liraglutide ndi jakisoni wopangidwa kamodzi patsiku wa incretin (metabolic hormone) glucagon-like peptide-1 (GLP-1), pochiza matenda amtundu wa 2 kapena kunenepa kwambiri.
Type 2 shuga mellitus
Liraglutide imathandizira kuwongolera shuga m'magazi. Kuchedwetsa kutulutsa m'mimba, komanso kupondereza katulutsidwe ka prandial glucagon.
Zofanana ndi madigiri osiyanasiyana ndi ma GLP-1 receptor agonists, liraglutide ili ndi zabwino kuposa njira zochiritsira zamtundu wa 2 shuga: +
Ili ndi kuthekera koletsa apoptosis ndikulimbikitsa kusinthika kwa maselo a beta (zowoneka m'maphunziro a nyama).
Amachepetsa chilakolako cha kudya ndikulepheretsa kulemera kwa thupi, monga momwe phunziro lamutu ndi mutu likuwonekera motsutsana ndi glimepiride.
Amachepetsa milingo ya triglyceride m'magazi.
Kunenepa kwambiri
Liraglutide yavomerezedwa ngati jekeseni wowonjezera pazakudya zopatsa mphamvu zama calorie komanso kuchuluka kwa masewera olimbitsa thupi pakuwongolera kulemera kwa odwala akuluakulu. Zomwe zatchulidwazi ndizoyambira thupi la thupi (BMI) la 30 kg/m2 kapena kukulirapo (obese), kapena 27 kg/m2 kapena kupitilira apo (kunenepa kwambiri), pamaso pa matenda amodzi okhudzana ndi kunenepa kwambiri (mwachitsanzo, kuthamanga kwa magazi), Type 2 shuga mellitus, kapena dyslipidemia). Chakumapeto kwa 2014, deta idanenedwa kuchokera ku mayeso a SCALE ™ Obesity ndi Prediabetes, omwe amayesa mwachisawawa, osawona kawiri, oyendetsedwa ndi placebo, amitundu yosiyanasiyana mwa anthu omwe alibe matenda a shuga omwe ali ndi kunenepa kwambiri komanso omwe alibe matenda a shuga omwe ali onenepa kwambiri ndi comorbidities. Muyeso wa gawo la 3ali, panali otenga nawo gawo 3,731 omwe adalandira chithandizo cha liraglutide 3 mg kapena placebo, onse kuphatikiza zakudya ndi masewera olimbitsa thupi. Omwe adamaliza kuyesa kwa masabata a 56 adapeza kulemera kwapakati pa 9.2%, kufananizidwa ndi kuchepa kwa 3.5% pagulu la placebo.
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