CAS 204656-20-2 Liraglutide China fakitale yabwino kwambiri malonda mwachindunji High Purity Safety kutumiza mkulu Quality mtengo woyenera mtengo wokwera mtengo kukhutira Kutumiza Mwachangu

Liraglutide, lipopeptide ndi polypeptide, ndi analogue ya GLP-1 yaumunthu momwe zotsalira za lysine zomwe zili pamalo 27 zimasinthidwa ndi arginine ndi gulu la hexadecanoyl lomwe limamangiriridwa ku lysine yotsalayo kudzera mu spacer ya glutamic acid. Amagwiritsidwa ntchito limodzi ndi zakudya komanso masewera olimbitsa thupi kuti apititse patsogolo glycemic control mwa akulu omwe ali ndi matenda a shuga a 2. Liraglutide imagwira ntchito ngati glucagon-ngati peptide-1 receptor agonist ndipo imagwira ntchito ngati neuroprotective agent.

Lumikizanani nafe

tsatanetsatane wazinthu

kulongedza & kutumiza

Mafotokozedwe Akatundu

Liraglutide ndi GLP-1 (1-37) yosinthidwa ku Ly: gulu la -amino ndi acylated ndi (N-hexadecanoyl) glutam- -yl moiety yomwe mosagwirizana koma mwachangu imamanga ku seramu ya seramu yamunthu. (Komanso, Lys amalowetsedwa m'malo ndi Arg.) Zosinthazi zimapereka kuchuluka kwa seramu T1?2 ya maola 10 mpaka 15 pambuyo pa kuwongolera kwa sc (0.6-1.8 mg), kulola kumwa kamodzi patsiku.Liraglutide (Victoza, Novo Nordisk) ikuyembekezera kuvomerezedwa ndi FDA, EMEA, ndi Koˉ roˉ -shoˉ (Japan).

vidiyo yamalonda

Product Application

Liraglutide ndi mtundu watsopano wa mankhwala a hypoglycemic omwe amayatsa AMP-activated protein kinase motero kumapangitsa chidwi cha insulin. Simangokhala ndi mphamvu yayikulu ya hypoglycemic, komanso imakhala ndi ntchito zochepetsera thupi, kuchepetsa kuthamanga kwa magazi, komanso kuwongolera mbiri yamagazi a lipid.

Liraglutide, glucagon-ngati peptide-1 (GLP-1) receptor agonist, amachepetsa kutulutsa m'mimba, amawonjezera kukhuta, komanso amachepetsa kudya kwa odwala, pomwe amachepetsa chikhumbo chaubongo chofuna kudya ndikulola thupi kuti liziwonjezera mphamvu zogwiritsa ntchito mphamvu kumathandizira kulemera. kutayika; amalepheretsa chiwindi kupanga shuga wambiri komanso kulimbikitsa kapamba kuti apange insulin yochulukirapo kuti achepetse shuga m'magazi; Kuphatikiza apo, liraglutide ilinso ndi phindu pamtima komanso chitetezo cha impso.

tsatanetsatane wazinthu

Dzina Lonse	Liraglutide
Nambala ya CAS	204656-20-2
Molecular Formula	C172H265N43O51
Kulemera kwa Maselo	3751.20000
PSA	1513.76000
LogP	6.12960
Malingaliro a kampani EINECS	810-818-7