0102030405
Ụlọ ọrụ na-enye ire ere na-ekpo ọkụ CAS 218949-48-5 Tesamorelin nwere ọnụ ahịa ọnụ ahịa dị elu dị elu na-ere ọkụ na-ebufe ọnụ ụzọ n'ọnụ ụzọ.
nkọwapụta ngwaahịa
| Aha nkịtị | Tesamorelin |
| Nọmba CAS | 218949-48-5 |
| Ibu molekụla | 5135.86 |
| Usoro ihe omimi | C221H366N72O67S |
| EINECS | 603-809-2 |
| Njupụta | N/A |
| Ebe esi nri | N/A |
| Ebe mgbari | N/A |
| Ọnọdụ nchekwa | Igwe nju oyi 2-8 Celsius |
Video ngwaahịa
Eji ngwaahịa
Timorelin nwere usoro amino acid 44 nke ihe na-ewepụta homonụ uto mmadụ (GRF), yana 3- hexenyl jikọtara ya na tyrosine N-terminal residue. Ọ bụ ihe analog nke na-ewepụta ihe na-emepụta ihe na-eto eto, nke nwere ike ọ bụghị naanị weghachi ihe nzuzo nke homonụ na-eto eto na vivo, kamakwa belata mmụba nke anụ ahụ adipose visceral (VAT), meziwanye dyslipidemia na ndụ ndụ, ma nọgide na-enwe ike itule. glucose na vivo. Timorelin bụ analọgụ sịntetik nke ihe na-ewepụta homonụ uto (GRF). Yiri GRF endogenous, ọ na-eme na vitro site na ijikọ na ịgbalite GRF nnata. GRF bụ polypeptide na-achịkwa hypothalamic, nke nwere ike ime ka mkpụrụ ndụ hormone na-eto eto pituitary na-emepụta ma hapụ hormone uto endogenous (GH). GH na-arụ ọrụ ọgwụ site na mmekọrịta ya na ndị na-anabata mkpụrụ ndụ ebumnuche, gụnyere chondrocytes, osteoblasts, cardiomyocytes, hepatocytes na adipocytes. Ọ dị mma maka ọgwụgwọ nke adiposity abdominal na ndị ọrịa bu nje HIV nwere lipodystrophy.
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