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CAS 204656-20-2 Liraglutide China ọmarịcha ụlọ ọrụ mmepụta ihe na-ere ahịa ozugbo High ịdị ọcha nchekwa mbupu oke mma kwesịrị ekwesị ọnụ ahịa ọnụ ahịa dị elu afọ ojuju nnyefe ngwa ngwa
Nkọwa ngwaahịa
Liraglutide bụ GLP-1 (1-37) emeziri na Ly: otu -amino ka ejiri otu (N-hexadecanoyl) glutam--yl acylated nke na-enweghị mmasị na-ejikọta ya na serum albumin nke mmadụ. (Ọzọkwa, Lys bụ conservatively dochie na Arg.) Mgbanwe ndị a na-enye maka a ukwuu extendedserum t1?2 nke 10 ka 15 awa mgbe sc nchịkwa (0.6-1.8 mg), ikwe maka otu ugboro kwa ụbọchị dosing. Liraglutide (Victoza, Novo Nordisk) na-eche nkwado nke FDA, EMEA, na Koˉ roˉ -shoˉ (Japan).
vidiyo ngwaahịa
Ngwa ngwaahịa
Liraglutide bụ ụdị ọgwụ hypoglycemic ọhụrụ na-eme ka protein kinase na-arụ ọrụ AMP wee na-eme ka insulin nwee mmetụta. Ọ bụghị naanị na ọ nwere mmetụta hypoglycemic dị ịrịba ama, kamakwa ọ nwere ọrụ nke mbelata ibu, mbelata ọbara mgbali, na mmelite nke profaịlụ lipid ọbara.
Liraglutide, onye na-anabata glucagon-dị ka peptide-1 (GLP-1), na-ebelata ịwụfu afọ, na-abawanye satiety, na-ebelata iri nri onye ọrịa, ebe ọ na-ebelata agụụ ụbụrụ nke iri nri na ikwe ka ahụ nwee ike ịba ụba ume na-ekere òkè na ibu ibu. mfu; ọ na-egbochi imeju iwepụta oke glucose ma na-akwalite pancreas imepụta insulin karịa iji belata shuga ọbara; na mgbakwunye, liraglutide nwekwara uru obi na nchekwa akụrụ.
nkọwapụta ngwaahịa
| Aha nkịtị | Liraglutide |
| Nọmba CAS | 204656-20-2 |
| Usoro ihe omimi | C172H265N43O51 |
| Ibu molekụla | 3751.20000 |
PSA | 1513.76000 |
LogP | 6.12960 |
EINECS | 810-818-7 |
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