Factory muag ncaj qha Pregabalin CAS 148553-50-8 nrog qhov zoo tshaj plaws thiab tus nqi qis tshaj hauv Tshuag muaj kev nyab xeeb thiab ceev tus me nyuam kws tshuaj nruab nrab

Pregabalin yog ib qho tshuaj uas poob rau hauv chav kawm ntawm cov tshuaj tiv thaiv kab mob. Pregabalin yog ib tug derivative ntawm gamma-aminobutyric acid (GABA), ib tug neurotransmitter nyob rau hauv lub hauv paus paj hlwb. Raws li txoj cai, nws muaj feem xyuam rau inhibitory neurotransmitter GABA, tab sis nws cov txheej txheem ntawm kev ua yog txawv. Nyob rau hauv cov nqe lus ntawm lub cev khoom, pregabalin yog dawb crystalline khoom. Nws cov yam ntxwv solubility suav nrog kev ua haujlwm tsis zoo hauv dej thiab soluble dawb hauv cov kuab tshuaj organic polar. Pregabalin muaj nyob rau hauv daim ntawv qhia qhov ncauj, xws li tshuaj ntsiav lossis ntsiav tshuaj, rau kev siv tshuaj.

Pregabalin feem ntau yog siv los kho ntau yam mob, nrog rau mob neuropathic, fibromyalgia, thiab qee yam qaug dab peg. Nws siv nws txoj kev kho mob los ntawm kev khi rau alpha-2-delta subunit ntawm voltage-gated calcium channels hauv nruab nrab paj hlwb. Qhov kev sib khi no ua rau kev nkag mus ntawm calcium ions, txo qhov tso tawm ntawm cov neurotransmitters, thiab yog li txo qis excitability ntawm paj hlwb.