CAS 204656-20-2 Liraglutide Tuam Tshoj zoo heev Hoobkas ncaj muag High Purity Safety shipping siab Zoo zoo tus nqi siab costomers siab ceev xa khoom

Liraglutide, lipopeptide thiab polypeptide, yog ib qho analogue ntawm tib neeg GLP-1 nyob rau hauv uas cov lysine residue ntawm txoj hauj lwm 27 yog hloov los ntawm arginine thiab ib pawg hexadecanoyl txuas rau cov lysine ntxiv ntawm glutamic acid spacer. Nws yog siv nrog kev noj haus thiab kev tawm dag zog los txhim kho glycemic tswj hauv cov neeg laus uas muaj ntshav qab zib hom 2. Liraglutide ua haujlwm raws li glucagon-zoo li peptide-1 receptor agonist thiab ua haujlwm ua tus neeg saib xyuas neuroprotective.

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Product Description

Liraglutide yog GLP-1(1–37) hloov kho ntawm Ly: pawg -amino yog acylated nrog ib qho (N-hexadecanoyl) glutam- -yl moiety uas noncovalently tab sis avidly khi tohuman serum albumin. (Tsis tas li ntawd, Lys yog conservatively hloov nrog Arg.) Cov kev hloov no muab rau ib tug zoo heev extensionserum t1?2 ntawm ~ 10 mus rau 15 teev tom qab sc kev tswj hwm (0.6–1.8 mg), tso cai rau noj ib hnub ib zaug.Liraglutide (Victoza, Novo Nordisk). tab tom tos kev pom zoo los ntawm FDA, EMEA, thiab Koˉ roˉ -shoˉ (Nyiv).

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Liraglutide yog ib hom tshuaj hypoglycemic tshiab uas ua rau AMP-activated protein kinase yog li txhim kho cov tshuaj insulin. Nws tsis tsuas yog muaj cov nyhuv hypoglycemic tseem ceeb, tab sis kuj muaj lub luag haujlwm ntawm kev poob phaus, txo cov ntshav siab, thiab txhim kho cov ntshav lipid profile.

Liraglutide, ib tug tib neeg glucagon-zoo li peptide-1 (GLP-1) receptor agonist, slows gastric emptying, tsub kom satiety, thiab txo tus neeg mob noj, thaum txo lub hlwb lub siab xav noj thiab tso cai rau lub cev kom nce lub zog siv plays lub luag hauj lwm nyob rau hauv hnyav. poob; nws tiv thaiv lub siab los ntawm kev tsim cov piam thaj ntau dhau thiab txhawb lub txiav ua kom cov tshuaj insulin ntau dua kom txo cov ntshav qab zib; Tsis tas li ntawd, liraglutide kuj muaj cov txiaj ntsig ntawm lub plawv thiab lub raum tiv thaiv.