ʻO ka hale kūʻai kūʻai pololei ʻo Pregabalin CAS 148553-50-8 me ka maikaʻi maikaʻi loa a me ke kumu kūʻai haʻahaʻa loa i ka waihona palekana a me ka lawe wikiwiki ʻana i ka lāʻau lapaʻau waena.

ʻO Pregabalin kahi lāʻau lapaʻau i hāʻule ma lalo o ka papa o nā lāʻau anticonvulsant. ʻO Pregabalin kahi mea i loaʻa i ka gamma-aminobutyric acid (GABA), kahi neurotransmitter i loko o ka ʻōnaehana nūnū waena. Ma ke ʻano, pili ia i ka GABA neurotransmitter inhibitory, akā ʻokoʻa kona ʻano hana. Ma keʻano o nā waiwai kino, he paʻa keʻokeʻo keʻokeʻo ka pregabalin. ʻO kāna mau hiʻohiʻona hiki ke hoʻoheheʻe ʻia me ka hiki ʻole ke hoʻoheheʻe ʻia i loko o ka wai a hiki ke hoʻoheheʻe ʻia i loko o nā mea hoʻoheheʻe organik polar. Loaʻa ka Pregabalin i loko o nā ʻano o ka waha, e like me nā capsules a i ʻole nā ​​papa, no ka hoʻohana lāʻau.

Hoʻohana pinepine ʻia ʻo Pregabalin e mālama i nā ʻano olakino like ʻole, me ka ʻeha neuropathic, fibromyalgia, a me kekahi mau ʻano o ka hopu ʻana. Hoʻohana ʻo ia i kāna mau hopena lapaʻau ma o ka hoʻopaʻa ʻana i ka subunit alpha-2-delta o nā kahawai calcium i hoʻopaʻa ʻia i ka uila i loko o ka ʻōnaehana nerve waena. Hoʻololi kēia hoʻopaʻa ʻana i ka komo ʻana o nā ion calcium, e hōʻemi ana i ka hoʻokuʻu ʻana o nā neurotransmitters, a ma laila e hoʻemi ai i ka excitability o nā pūnana nerve.