Hāʻawi ka hale hana i nā kūʻai wela CAS 218949-48-5 Tesamorelin me ke kumukūʻai kūʻai kūʻai kūʻai kiʻekiʻe kiʻekiʻe a me ka lawe ʻana i ka puka i ka puka.

Hoʻokumu ʻia ʻo Timorelin me 44 amino acid sequences o ke kanaka growth hormone releasing factor (GRF), me 3-hexenyl i hoʻopili ʻia i kona koena tyrosine N-terminal. He mea hou ia e hoʻokuʻu ana i ka hormone ulu ana analog, ʻaʻole hiki ke hoʻihoʻi i ka mea huna maʻamau o ka hormone ulu i loko o ka vivo, akā e hōʻemi hoʻi i ka piʻi ʻana o ka visceral adipose tissue (VAT), hoʻomaikaʻi i ka dyslipidemia a me ka maikaʻi o ke ola, a mālama i ke koena ikaika o ka. glucose i loko o vivo. ʻO Timorelin kahi analogue synthetic o ka growth hormone releasing factor (GRF). E like me ka GRF endogenous, hana ia in vitro ma o ka hoʻopaʻa ʻana a me ka hoʻoulu ʻana i nā mea loaʻa GRF. ʻO GRF kahi polypeptide hoʻoponopono hypothalamic, hiki ke hoʻoulu i nā cell hormone ulu pituitary e synthesize a hoʻokuʻu i ka hormone ulu ulu (GH). Hoʻokani ka GH i kahi hana pharmacological ma o ka launa pū ʻana me nā mea loaʻa kikoʻī o nā cell target, me nā chondrocytes, osteoblasts, cardiomyocytes, hepatocytes a me adipocytes. He kūpono ia no ka mālama ʻana i ka adiposity abdominal i nā maʻi maʻi HIV me ka lipodystrophy.