CAS 1451-83-8 Kina mea hana maikaʻi loa kūʻai pololei kiʻekiʻe ʻO ka hoʻouna wikiwiki kiʻekiʻe kiʻekiʻe nā mea kūʻai aku ʻoluʻolu ka palekana i ka hoʻouna ʻana i ke kumu kūʻai kūpono.

ʻO Pregabalin (Lyrica), kahi derivative o GABA e pili kokoke ana i ka gabapentin, ua hana i ka noiʻi nui no kona pono i ka mālama ʻana i nā kūlana e like me ka generalized anxiety disorder (GAD), fibromyalgia, neuropathic ʻeha, a me nā ʻāpana paʻakikī. Me he mea lā ua ʻoi aku ka hopena i manaʻo ʻia ma ka subunit a2-δ o nā kahawai calcium i loko o ka lolo i hoʻohālikelike ʻia me gabapentin. Ua ʻae ʻia ʻo Pregabalin i ka FDA i ka hopena o 2004 no ka mālama ʻana i ka ʻeha neuropathic a me ka epilepsy. Ma 2008, lilo ia i lāʻau lapaʻau mua i ʻae ʻia no ka mālama ʻana i ka fibromyalgia. ʻOiai ua ʻae ʻia ka pregabalin no ka mālama ʻana i ka GAD ma ka European Union ma 2006, ʻaʻole i loaʻa iā ia ka ʻae FDA no GAD ma ʻAmelika Hui Pū ʻIa e like me ka manawa i kākau ai.