Mai ƙera Babban Tsabta 98% Peptides Foda Liraglutide CAS 204656-20-2 Peptides Foda a cikin Vials ƙarancin farashi peptides kyawawan kayan kwalliyar kayan kwalliya

Liraglutide (NN2211) wani agonist mai karɓa ne na glucagon-kamar peptide-1 mai tsayi. An sayar da shi a ƙarƙashin sunan alamar Victoza, magani ne na allura wanda Novo Nordisk ya samar don maganin ciwon sukari na 2. A cikin 2015, Novo Nordisk ya fara tallata shi a cikin Amurka a ƙarƙashin sunan alamar liraglutide azaman magani ga kiba a cikin manya tare da aƙalla yanayin haɗaɗɗun nauyi guda ɗaya.

Amfanin Likita

Liraglutide wani nau'in allura ne na yau da kullun na ɗan adam incretin (hormone metabolic) glucagon-kamar peptide-1 (GLP-1), don maganin ciwon sukari na 2 ko kiba.

Nau'in ciwon sukari na 2

Liraglutide yana inganta sarrafa glucose na jini. Jinkirta zubewar ciki, da kuma danne fitar glucagon prandial.

Dangane da digiri daban-daban tare da sauran agonists masu karɓa na GLP-1, liraglutide yana da fa'ida akan ƙarin magungunan gargajiya don nau'in ciwon sukari na 2:

Yana da yuwuwar hana apoptosis da haɓaka haɓakar ƙwayoyin beta (wanda aka gani a nazarin dabba).

Yana rage ci kuma yana hana kiba, kamar yadda aka nuna a binciken kai-da-kai da glimepiride.

Yana rage matakan triglyceride na jini.

Kiba

An yarda da Liraglutide azaman haɗin allura zuwa rage rage-kalori rage cin abinci da ƙara yawan motsa jiki don sarrafa nauyi na yau da kullun a cikin manya marasa lafiya. Sharuɗɗan ƙayyadaddun ƙayyadaddun ƙayyadaddun ƙayyadaddun ƙayyadaddun ma'aunin jiki ne na farko (BMI) na 30 kg/m2 ko mafi girma (kiba), ko 27 kg/m2 ko mafi girma (kiba), a gaban aƙalla yanayin haɗaɗɗun nauyin nauyi ɗaya (misali hauhawar jini, nau'in ciwon sukari na 2, ko dyslipidemia). A ƙarshen 2014, an ba da rahoton bayanai daga gwaji na SCALE ™ Obesity da Prediabetes, wanda bazuwar, makafi biyu, mai sarrafa wuribo, gwaji na ƙasa da ƙasa a cikin mutanen da ba su da ciwon sukari tare da kiba da marasa ciwon sukari waɗanda ke da kiba tare da cututtuka. A cikin wannan gwaji na 3a, akwai mahalarta 3,731 da aka bazu don jiyya tare da liraglutide 3 MG ko placebo, duka a hade tare da abinci da motsa jiki. Wadanda suka kammala gwajin makonni 56 sun sami matsakaicin asarar nauyi na 9.2%, don a kwatanta su da raguwar 3.5% a cikin rukunin placebo.