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Pregabalin (Lyrica), wanda ya samo asali ne daga GABA wanda ke da alaƙa da gabapentin, ya gudanar da bincike mai zurfi don ingancinsa a cikin magance yanayi irin su rikice-rikice na tashin hankali (GAD), fibromyalgia, ciwon neuropathic, da kuma ɓarna mai rikitarwa. Yana da alama yana da ƙarin tasiri mai niyya akan sashin a2-δ na tashoshin calcium a cikin kwakwalwa idan aka kwatanta da gabapentin. An ba da Pregabalin izinin FDA a ƙarshen 2004 don maganin ciwon neuropathic da epilepsy. A cikin 2008, ya zama magani na farko da aka amince da shi don gudanar da fibromyalgia. Kodayake an amince da pregabalin don maganin GAD a cikin Tarayyar Turai a cikin 2006, har yanzu bai sami amincewar FDA ga GAD a Amurka ba har zuwa lokacin rubutawa.